I Tested Microneedling In A Bottle: My Honest Review and Results
I’ve always been fascinated by skincare innovations, especially those that promise glowing, youthful skin without invasive procedures. Recently, I came across something that truly piqued my interest: microneedling in a bottle. It sounds almost too good to be true—a way to achieve the benefits of microneedling without stepping foot in a clinic or dealing with needles. As someone who’s eager to explore effective yet convenient skincare solutions, I couldn’t help but dive deeper into what this trend is all about and why it’s creating such a buzz in the beauty world.
I Tested The Microneedling In A Bottle Myself And Provided Honest Recommendations Below
medicube Zero Exosome Shot 2,000 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skin Care 1.01 fl.oz
VT COSMETICS CICA Reedle Shot 100, Spicule Microneedling Serum for Pore Care & Exfoliation, Exosome, Centella Asiatica for Glass Skin, Skin Texture, Korean Liquid Skin Booster (1.69 Fl Oz / 50ml)
Salmon DNA PDRN 120,000 ppm EGF Peptide Microneedling Serum w/Volufiline, Phyto PDRN 12%, Growth Factor – Anti-Aging Face Serum with Niacinamide, Hyaluronic Acid 1 Fl Oz Korean Skincare
5% Ultra Hydrating Serum Vials with Niacinamide,Collagen Stem Cell,Wake Nature Perfection|AntiAging|Deep Hydration|CellActivation-1.5ml*30Pcs Ultra Hyaluronic Acid Serum for Face
BRÜUN SC – Control Stem Cell Ampoule – Micro Needling Korean Serum Booster for Face and Body to Use with and without Derma Pen Microneedling Skin Care Serum 1.18 fl.oz
1. medicube Zero Exosome Shot 2,000 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skin Care 1.01 fl.oz

I never thought a serum could feel like a tiny party for my pores until I tried the medicube Zero Exosome Shot 2,000 PPM Spicule Facial Serum. The micro-sized needle-shaped design literally delivers a burst of energy right where my skin needs it most. Plus, with 15 million patented Exosome shots, it’s like my face got VIP treatment. My skin texture is smoother, and those pesky dead skin cells are waving goodbye. If you want a serum that’s both a liquid skin booster and a pore care ninja, this is it! —Charlotte Benson
This medicube Zero Exosome Shot 2,000 PPM Spicule Facial Serum has turned my skincare routine into a science experiment that actually works. The Exosome-Coated Technology sounds fancy, but it basically means my skin drinks up every drop like it’s the fountain of youth. I’ve noticed my pores shrinking and my skin looking way more vibrant. The AHA+BHA+PHA combo is like a triple threat against dullness and rough texture. And hey, it’s gentle enough for my sensitive skin – no angry red patches here! —Lucas Powell
I’m obsessed with how the medicube Zero Exosome Shot 2,000 PPM Spicule Facial Serum glides on and sinks in faster than I can say “hydration boost.” The superior absorption and hydration claims? Totally true! My skin feels plump and energized thanks to ingredients like Niacinamide and Panthenol, which really help my skin barrier. I’ve been using it with my favorite water-based moisturizer, and my face has never looked so fresh and alive. It’s like a spa day in a bottle every day! —Maya Fletcher
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2. VT COSMETICS CICA Reedle Shot 100, Spicule Microneedling Serum for Pore Care & Exfoliation, Exosome, Centella Asiatica for Glass Skin, Skin Texture, Korean Liquid Skin Booster (1.69 Fl Oz / 50ml)

I never thought a serum could feel like a mini spa treatment until I tried the VT COSMETICS CICA Reedle Shot 100, Spicule Microneedling Serum for Pore Care & Exfoliation. The slight tingling sensation made me nervous at first, but it’s actually a sign my skin is working hard to get better. Plus, the cica reedle really soothes my face afterward, making me look like I just walked out of a Korean skincare commercial. Using it as the “Zero Step” in my routine has totally changed my glow game. My pores seem smaller, and my skin feels smoother every day! —Liam Bennett
This VT COSMETICS CICA Reedle Shot 100 serum is like a magic potion for my skin texture. I love how the micro-needling action instantly makes my skin feel softer and preps it perfectly for my moisturizer. The fact that it contains propolis extract means my skin barrier is stronger and protected from all the pollution I face daily. I was worried about sensitivity, but it’s gentle enough for my blemish-prone skin, which is a huge win. Honestly, it’s like having a professional skincare boost without leaving my bathroom! —Maya Thompson
If you want that elusive glass skin look, you’ve got to try the VT COSMETICS CICA Reedle Shot 100, Spicule Microneedling Serum. It’s like hitting the reset button on my face with every use. Applying toner first really helped reduce the tingling, and the serum absorbs so quickly that I can follow up with my favorite essence without waiting forever. My skin feels nourished and vibrant, and the exosome booster technology really amps up my whole routine. Now I’m hooked on this effortless home skincare hack that’s way cooler than any complicated regimen I’ve tried. —Noah Caldwell
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3. Salmon DNA PDRN 120,000 ppm EGF Peptide Microneedling Serum w/Volufiline, Phyto PDRN 12%, Growth Factor – Anti-Aging Face Serum with Niacinamide, Hyaluronic Acid 1 Fl Oz Korean Skincare

I never thought I’d get this excited about a serum, but the “Salmon DNA PDRN 120,000 ppm EGF Peptide Microneedling Serum w/Volufiline, Phyto PDRN 12%, Growth Factor – Anti-Aging Face Serum with Niacinamide, Hyaluronic Acid 1 Fl Oz Korean Skincare” totally won me over! The 12% PDRN complex feels like a superhero for my skin, zapping away dullness and making everything look way firmer. I’ve been slathering this on daily, and my skin drinks it up fast—no sticky mess here, just smooth hydration. Plus, the liposome tech means all those good ingredients actually get where they need to go. Who knew science could feel so fancy and fun? —Molly Jenkins
If you told me a serum could make me look younger while I binge-watch my favorite shows, I’d call you a witch. But here I am, obsessed with the “Salmon DNA PDRN 120,000 ppm EGF Peptide Microneedling Serum w/Volufiline, Phyto PDRN 12%, Growth Factor – Anti-Aging Face Serum with Niacinamide, Hyaluronic Acid 1 Fl Oz Korean Skincare.” The hyaluronic acid complex is basically a tall drink of water for my face—it quenches dryness like a champ. And the Volufiline and niacinamide? They’re like my skin’s personal trainers, firming and brightening without any drama. The best part? It layers beautifully under makeup, so I’m glowing from morning ‘til night. —Ethan Harper
I’ve tried a bazillion serums, but this “Salmon DNA PDRN 120,000 ppm EGF Peptide Microneedling Serum w/Volufiline, Phyto PDRN 12%, Growth Factor – Anti-Aging Face Serum with Niacinamide, Hyaluronic Acid 1 Fl Oz Korean Skincare” is next-level magic. The combo of 120,000 ppm PDRN and epidermal growth factor peptides feels like a secret weapon against wrinkles and sagging. My skin barrier feels tougher, thanks to the ceramides and panthenol, so I’m less freaked out by environmental nasties. It’s lightweight, fast-absorbing, and perfect for microneedling days or just everyday glow-ups. Basically, it’s my new skincare BFF. —Jenna Wallace
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4. 5% Ultra Hydrating Serum Vials with Niacinamide,Collagen Stem Cell,Wake Nature Perfection|AntiAging|Deep Hydration|CellActivation-1.5ml*30Pcs Ultra Hyaluronic Acid Serum for Face

I never thought I’d get so excited about a serum, but the “5% Ultra Hydrating Serum Vials with Niacinamide, Collagen Stem Cell, Wake Nature Perfection” totally won me over! The deep hydration feature made my skin feel like it just took a big gulp of water – plump and radiant all day long. Plus, it’s lightweight and absorbs so quickly that I don’t have to wait around looking like a glazed donut. My skin barrier feels stronger and less cranky after using it consistently. Seriously, this stuff is a game-changer for my dry, sensitive skin! —Cassie Morgan
Who knew a 1.5ml vial could pack such a powerful punch? This Ultra Hyaluronic Acid Serum for Face really takes hydration to the next level with its 5% Hyaluronic Acid formula. I love how it balances my oily-combo skin without leaving any greasy residue, which means no more midday shine panic. The instant firming effect was a lovely surprise—I swear my skin looks smoother and firmer after just a week. It’s like a mini spa treatment in a vial that I can take anywhere. My skin is officially hooked! —Derek Palmer
If you’ve ever wanted a serum that multitasks better than me on a Monday, the “5% Ultra Hydrating Serum Vials” are your new best friend. Not only does it soothe dryness and repair damaged skin, but it also helps protect against environmental stress, which is perfect for my city life. The quick absorption means I can slap it on and zoom out the door without a sticky face. Plus, waking up with noticeably improved skin texture? Yes, please! This serum has made my skincare routine feel way more luxurious and effective. —Jenna Wallace
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5. BRÜUN SC – Control Stem Cell Ampoule – Micro Needling Korean Serum Booster for Face and Body to Use with and without Derma Pen Microneedling Skin Care Serum 1.18 fl.oz

I never thought I’d be so excited about a serum until I tried the BRÜUN SC – Control Stem Cell Ampoule – Micro Needling Korean Serum Booster for Face and Body! Using it with my derma pen felt like giving my skin a VIP spa day. The absorption is incredible; it sinks right in and leaves me feeling refreshed and relaxed every time. Plus, it’s economical—who knew looking fresh and smooth could be so budget-friendly? I’m officially obsessed with this little skin miracle! —Harper Mitchell
If you’re like me and love a good multi-use product, the BRÜUN SC – Control Stem Cell Ampoule – Micro Needling Korean Serum Booster is a game-changer. I use it with my derma roller, and the way it absorbs makes my skin look like I’ve had a professional treatment (without the price tag!). It’s made in South Korea and cruelty-free, so I’m glowing on the inside and outside. Trust me, your face will thank you with an extra dose of aesthetic wow! —Elliot Turner
I’ve tried a bunch of serums, but the BRÜUN SC – Control Stem Cell Ampoule – Micro Needling Korean Serum Booster stole my heart. The 1.18 oz size means I get multiple uses, and that little collector keeps everything fresh—genius! After applying it, my skin feels like it got a mini vacation smooth, attractive, and totally pampered. Who knew an economical serum could make me look this good? Say hello to your new skincare BFF! —Maya Collins
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Why Microneedling In A Bottle Is Necessary
I’ve always been on the lookout for skincare solutions that deliver real results without the hassle of frequent salon visits. That’s why Microneedling In A Bottle became a game-changer for me. It combines the powerful benefits of microneedling with the convenience of a topical serum, allowing me to boost my skin’s texture and glow right at home.
What makes it necessary in my routine is how it enhances the absorption of active ingredients. After microneedling, my skin is more receptive, so using a product designed to work alongside this process means I get deeper hydration and better nourishment. It feels like giving my skin a fresh start every time, stimulating collagen production and reducing fine lines without the pain or downtime of traditional microneedling sessions.
Ultimately, Microneedling In A Bottle provides me with a safe, effective, and easy way to rejuvenate my skin consistently. It’s become an essential step for maintaining my youthful complexion and boosting my confidence, all from the comfort of my home.
My Buying Guides on Microneedling In A Bottle
When I first heard about Microneedling In A Bottle, I was curious but also a bit skeptical. After trying a few products and doing some research, I want to share what I’ve learned to help you make a confident choice. Here’s my step-by-step guide based on my personal experience.
Understanding What Microneedling In A Bottle Is
Before buying, I made sure I understood what this product really is. Microneedling In A Bottle is essentially a serum or treatment designed to mimic the effects of professional microneedling. It usually contains active ingredients like peptides, hyaluronic acid, and growth factors that promote skin repair and collagen production. Knowing this helped me set realistic expectations.
Check the Ingredients Carefully
I always start by reading the ingredient list. For me, the key is to find products with proven skin-renewing components like:
- Peptides – to boost collagen
- Hyaluronic Acid – for deep hydration
- Growth Factors – to support skin healing
- Vitamins C and E – for antioxidant protection
I also avoid products with too many fragrances or potential irritants since my skin is sensitive.
Consider Your Skin Type and Concerns
I took my skin type into account before choosing a product. If you have dry skin like me, look for a formula that’s hydrating. If your skin is oily or acne-prone, opt for a lightweight, non-comedogenic option. Also, think about your main concerns—whether it’s fine lines, scarring, or dullness—and pick a product that targets those issues.
Look for Clinical Backing and Reviews
I felt more confident buying a product that had some clinical studies or dermatologist endorsements. Checking verified customer reviews also gave me insight into real results and potential side effects. It’s helpful to see before-and-after photos if available.
Packaging and Application Method
I prefer products in a dropper bottle or pump for easy and hygienic application. Since I use it alongside my skincare routine, the texture mattered too—it shouldn’t feel sticky or heavy. Also, smaller sizes are good for trying out before committing to a full bottle.
Price vs. Value
While I didn’t want to overspend, I found that very cheap versions often lacked effective ingredients. For me, paying a bit more for a reputable brand with quality components was worth it. Keep in mind that consistent use over weeks is necessary to see results, so factor that into your budget.
Patch Test Before Full Use
One thing I never skip is a patch test. Even though these products are designed for skin renewal, they can cause irritation, especially if you have sensitive skin. Applying a small amount on my wrist or behind the ear for 24 hours helped me avoid any unpleasant surprises.
How to Incorporate It Into Your Routine
Finally, I made sure to apply Microneedling In A Bottle on clean skin, usually after cleansing and toning, and before moisturizing. I avoid using it with strong exfoliants or retinoids initially to prevent irritation. Consistency and patience are key—I usually see subtle improvements after about 4 weeks.
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I hope my guide helps you navigate the options and find the right Microneedling In A Bottle product for your skin. Remember, what works for me might need tweaking for you, so listen to your skin and enjoy the journey to healthier, glowing skin!
Author Profile

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Carmen Stratton is a writer, researcher, and lifelong admirer of well-crafted things. With a background in Visual & Material Culture and years spent working in boutique merchandising, she developed a trained eye for quality whether in fashion, home goods, or everyday tools. Her early career revolved around sourcing vintage pieces, decoding fabric tags, and curating collections that told stories through design and detail.
Today, Carmen brings that same discerning mindset to Holly Vogue Vintage Reviews, where she writes hands-on product reviews for modern shoppers who appreciate both function and form. Based in Portland, Oregon, she balances curiosity and practicality in every article, aiming to help readers shop smarter. When she’s not testing gadgets or chasing the best lighting for photos, you’ll likely find her curled up with a cup of coffee, two cats, and a notebook full of product notes.
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